Prudence Crandall (September 3, 1803 – January 27, 1890) was an American schoolteacher and activist. She ran the Canterbury Female Boarding School in Canterbury, Connecticut, which became the first known school for African American girls ("young Ladies and little Misses of color") in the United States led by a white woman. She was the sister of Reuben Crandall, the defendant in the Trial of Reuben Crandall.
In 1832, when Crandall admitted Sarah Harris, a 20-year-old African American woman, to her school, she created what can be considered the first known integrated classroom in the United States. Following the decision, parents of white students began to withdraw their daughters.