Lucrezia Borgia (18 April 1480 – 24 June 1519) was an Italian noblewoman of the House of Borgia who was the illegitimate daughter of Pope Alexander VI and Vannozza dei Cattanei. She was a former governor of Spoleto.
Her family arranged several marriages for her that advanced their own political position, including to Giovanni Sforza, Lord of Pesaro and Gradara, Count of Cotignola; Alfonso of Aragon, Duke of Bisceglie and Prince of Salerno; and Alfonso I d'Este, Duke of Ferrara. Alfonso of Aragon was an illegitimate son of the King of Naples, and tradition has it that Lucrezia's brother Cesare may have had him murdered after his political value waned.
Notorious tales about her family have cast Lucrezia as a femme fatale, a controversial role in which she has been portrayed in many artworks, novels, and films.