Missouri is a landlocked state in the Midwestern region of the United States. Ranking 21st in land area, it borders Iowa to the north, Illinois, Kentucky and Tennessee to the east, Arkansas to the south and Oklahoma, Kansas, and Nebraska to the west. With over six million residents, it is the 19th-most populous state of the country. The largest urban areas are St. Louis, Kansas City, Springfield, and Columbia. The capital is Jefferson City.
Humans have inhabited present-day Missouri for at least 12,000 years. The Mississippian culture, which emerged in the ninth century, built cities with pyramidal and other ceremonial mounds before declining in the 14th century. The Indigenous Osage and Missouria nations inhabited the area when European people arrived in the 17th century.