SS Princess Alice, formerly PS Bute, was a British passenger paddle steamer that sank on 3 September 1878 after a collision with the collier SS Bywell Castle on the River Thames. Between 600 and 700 people died, all from Princess Alice, the greatest loss of life of any British inland waterway shipping accident. No passenger list or headcount was made, so the exact figure of deaths has never been known.
Built in Greenock, Scotland, in 1865, Princess Alice was employed for two years in Scotland before being purchased by the Waterman's Steam Packet Co to carry passengers on the Thames. By 1878 she was owned by the London Steamboat Co and was captained by William R. H.