Betty and Bob is a 1932-1940 radio soap opera. The soap opera follows the lives of Betty and Bob Drake. Betty was a secretary who falls madly in love with her boss, bachelor Bob Drake. The two wed and each day, the subject matter dealt with everything from love to hate, jealousy to divorce, murder to betrayal, and collusion to insanity.
The program was the first radio program produced by future daytime radio monarchs Frank and Anne Hummert. The program also began a long partnership between the Hummerts and scriptwriter Robert Hardy Andrews.
The program originally starred Elizabeth Reller and Don Ameche in the title roles of Betty and Bob Drake.